Publications
Publications, Books, Book Chapters and Reviews by Prof. Marcus Maurer, MD
Use: Start with an overview of all publications. Use tag links to list selected documents or to list an entire category, e.g. Original Work, Books, Book Chapters, Reviews. If you know what you are looking for, enter this term in the search field.
Treatment of acute attacks of hereditary angioedema (HAE) with the bradykinin B2 receptor antagonist icatibant
| Filename | 37. Magerl et al.,HAE B2 receptor,Rev. Port. de Imunoalerg.2010.pdf |
| Filesize | 161.74 KB |
| Version | r.037 |
| Date added | June 26, 2020 |
| Downloaded | 0 times |
| Category | Reviews |
| Tags | bradykinin, Hereditary Angioedema, Icatibant |
| Authors | Magerl, M., Keßler, B., and Maurer, M. |
| Citation | Magerl, M., Keßler, B., and Maurer, M.: Treatment of acute attacks of hereditary angioedema (HAE) with the bradykinin B2 receptor antagonist icatibant. Rev. Port. Imunoalergologia 2010: 18; 207-214. |
| Corresponding authors | Maurer, M. |
| DocNum | R.37 |
| DocType | |
| Edition; Page | 18; 207-214 |
| IF | N/A |
| Publisher | Rev. Port. Imunoalergologia |
| ReleaseDate | 2010 |
Icatibant is a selective and competitive bradykinin B2 receptor antagonist. It was approved in 2008, for the symptomatic treatment of acute attacks of hereditary angioedema (HAE) in adults with a deficiency of the C1 esterase inhibitor. Icatibant is the first subcutaneous treatment for HAE. The efficacy of icatibant in the treatment of moderate to very severe cutaneous and abdominal attacks in patients with HAE was investigated in two Phase III trials in comparison with tranexamic acid and with placebo, respectively. The time to onset of symptom relief, the primary end point of the trial, was significantly shortened with icatibant compared to tranexamic acid. Icatibant demonstrated a favourable safety profile in clinical trials with no drug-related serious adverse events.
(Last update: 07.2025)
| Number of original publications in peer-reviewed journals: | 650 |
| Number of reviews in peer-reviewed journals: | 229 |
| Number of publications (original work and reviews) in peer-reviewed journals: | 879 |
| Cumulative IF for original publications in peer-reviewed journals: | 4648.29 |
| Cumulative IF for reviews in peer-reviewed journals: | 1689.22 |
| Cumulative IF of publications (original work & reviews) in peer-reviewed journals: | 6761.91 |
| Total number of citations: 45,522 h-index: 109 (Web of Science July 2025) | 45,522 |
Download-Information
To be able to download the offered contents, you have to login. If you do not know the login, please write me your request.